The central dogma describes the flow of genetic information within a biological system. It was first stated by Francis Crick in 1958 and re-stated in a Nature paper published in 1970:
“The central dogma deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred back from protein to either protein or nucleic acid.”
In simple words, Central Dogma is the process in which
"DNA makes RNA makes protein"